Background. Surgical correction of mitral regurgitation (MR) can lead to postoperative low cardiac output state. We aimed to\nassess the acute hemodynamic changes after percutaneous MitraClip therapy (a unique model without influence of factors linked\nto surgical procedure) in patients with functional MR without the influence of general anaesthesia. Methods. We studied invasive\nhemodynamic parameters in 23 patients before procedure (conscious, nonsedated patients), during procedure (intubated patients),\nand the first day after MitraClip implantation (conscious, extubated patients). Results. Mitral valve clipping significantly increased\ncardiac index (CI) (from 2.0 �± 0.5 to 3.3 �± 0.6 L/min/m2;
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